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ÇöÀçÀ§Ä¡ : HOME > ¸®Æ÷Æ® > »ý¸í°øÇÐ > Á¦¾à
Biosimilars: Market Entry Strategies
¹ßÇà»ç Datamonitor

¹ßÇàÀÏ 2011-12
ºÐ·®
¼­ºñ½ºÇüÅ Report
ÆǸŰ¡°Ý

ÀμâÇϱâ
Table of Contents

EXECUTIVE SUMMARY

  • Introduction
  • Strategic scoping and focus
  • Key findings
  • Related reports

BIOSIMILARS OFFER A RELATIVELY LOW RISK GROWTH STRATEGY FOR PHARMA

  • Advantages for entering the biosimilar arena
    • Capture a share of the fast growing biosimilars market
    • Lower development costs and reduced risk of pipeline failures
    • Leverages the branded sales model
    • Biosimilars provide a more stable revenue stream
    • Biosimilars have the potential to increase profit margins for generics producers
  • External drivers of the biosimilars market
    • Growing use of biologic products
    • A number of blockbuster branded biologics will have expired by the end of 2016
    • The high cost of biologics will drive payers to look to biosimilars for cost-savings
    • Biosimilars have seen growing payer and patient acceptance
    • There are a growing number of navigable biosimilar approval pathways

BIOSIMILAR DEAL TRENDS

  • Interest in biosimilars varies among the top 50 pharma companies
    • Actively interested in biosimilars
    • Plan to enter the biosimilars arena
    • Will avoid biosimilars
  • Strategies used by the top 50 pharma companies to enter the biosimilars arena
    • In-house development, partnership and acquisition deals
    • Partnership and acquisition deals
    • Development and commercialization deals
    • Commercialization deals

LEADING PHARMA COMPANIES ACTIVE IN BIOSIMILARS

  • Merck & Co. (Merck BioVentures): four key deals have shaped its biosimilars capabilities
    • Biosimilar portfolio
    • Biosimilar deals and partnerships
  • Pfizer: deal with Biocon provides access to biosimilar insulins
    • Biosimilar portfolio
    • Biosimilar deals and partnerships
  • GlaxoSmithKline: opting for a cautious entry in biosimilars
    • Biosimilar portfolio
    • Biosimilar deals and partnerships
  • Biogen Idec: perceives the biosimilars market to be a low risk strategy to generate additional revenue
    • Biosimilar deals and partnerships
  • Amgen: deal with Watson marks Amgen¡¯s entrance into the biosimilars arena
    • Biosimilar deals and partnerships
  • Daiichi Sankyo (Ranbaxy): gains access to biosimilars via Ranbaxy
    • Biosimilar portfolio
    • Biosimilar deals and partnerships
  • Sandoz: biosimilar success shaped largely through its acquisition of Hexal
    • Biosimilar portfolio
    • Biosimilar deals and partnerships
  • Teva: acquisition of ratiopharm significantly bolstered biosimilar portfolio and capabilities
    • Biosimilar portfolio
    • Biosimilar deals and partnerships
  • Hospira: partnerships have enabled the company to build a considerable biosimilars portfolio
    • Biosimilar portfolio
    • Biosimilar deals and partnerships
  • Stada: turns to collaborations to share the costs and risks of developing biosimilars
    • Biosimilar portfolio
    • Biosimilar deals and partnerships
  • Apotex: collaboration with Intas provides access to biosimilar filgrastim candidates
    • Biosimilar portfolio
    • Biosimilar deals and partnerships
  • Watson: building upon its expertise in women¡¯s health by licensing in biosimilar infertility candidate
    • Biosimilar portfolio
    • Biosimilar deals and partnerships
  • Actavis: joint venture with Bioton provides access to biosimilar insulins
    • Biosimilar portfolio
    • Biosimilar deals and partnerships
  • Mylan: joins forces with Biocon to develop biosimilars
    • Biosimilar deals and partnerships

LEADING PHARMA COMPANIES LOOKING TO ENTER THE BIOSIMILARS MARKET

  • Boehringer Ingelheim: plans to capitalize on biopharmaceuticals contract manufacturing

LEADING PHARMA COMPANIES THAT DO NOT PLAN TO ENTER BIOSIMILARS

  • AstraZeneca: opts for biosuperiors rather than biosimilars
  • Bayer: sees no attraction in entering the biosimilars sector
  • Roche: determined to protect its leading biologics offering from biosimilar competition

BIBLIOGRAPHY

  • Publications and online articles
  • Datamonitor reports and products

APPENDIX

  • Exchange rates used in this report


TABLES

  • Table: Comparison of operating margins for branded biologics, branded prescription pharma, and generics companies, 2010
  • Table: Estimated savings anticipated to be gained through the use of biosimilar drugs
  • Table: Biosimilar and copy-biologic approval pathways
  • Table: Interest in biosimilars among branded companies ranked among the to 50 pharma companies
  • Table: Merck & Co. biosimilars portfolio, 2011
  • Table: Merck & Co. – deals targeting biosimilars
  • Table: Pfizer biosimilar/copy-biologic portfolio, 2011
  • Table: Pfizer deals targeting biosimilars
  • Table: GlaxoSmithKline biosimilars/copy-biologic portfolio, 2011
  • Table: GlaxoSmithKline deals targeting biosimilars
  • Table: Biogen Idec deals targeting biosimilars
  • Table: Amgen – deals targeting biosimilars
  • Table: Ranbaxy biosimilars/copy-biologic portfolio, 2011
  • Table: Ranbaxy deals targeting biosimilars
  • Table: Sandoz biosimilars portfolio, 2011
  • Table: Sandoz deals targeting biosimilars
  • Table: Teva biosimilars portfolio, 2011
  • Table: Teva deals targeting biosimilars
  • Table: Hospira biosimilars portfolio, 2011
  • Table: Hospira deals targeting biosimilars
  • Table: Stada biosimilars portfolio, 2011
  • Table: Stada deals targeting biosimilars
  • Table: Apotex biosimilars portfolio, 2011
  • Table: Apotex deals targeting biosimilars
  • Table: Watson biosimilars portfolio, 2011
  • Table: Watson deals targeting biosimilars
  • Table: Actavis biosimilars/copy-biologic portfolio, 2011
  • Table: Actavis – deals targeting biosimilars
  • Table: Mylan deals targeting biosimilars
  • Table: Currency exchange rates, 2011

FIGURES

  • Figure: Advantages for entering the biosimilars market and external factors driving biosimilar growth
  • Figure: Global biosimilar sales ($m), 2007–10
  • Figure: 2016 sales of biologics due to face patent expiry to 2016 for the top 50 pharma companies
  • Figure: Deals made by the top 50 pharma companies to access biosimilars as well as enhance their biologic capabilities , 1999–2011
  • Figure: Competencies and challenges in biosimilars development
  • Figure: Strategies used by leading pharma companies to directly access biosimilars
  • Figure: Types of deals made by the top 50 pharma companies to access biosimilars as well as enhance their biologic capabilities, 1999–2011
  • Figure: Merck & Co. forecast global sales according to molecule type, 2010–16
  • Figure: Pfizer forecast global sales according to molecule type, 2010–16
  • Figure: GlaxoSmithKline forecast global sales according to molecule type, 2010–16
  • Figure: Biogen Idec forecast global sales according to molecule type, 2010–16
  • Figure: Amgen forecast global sales according to molecule type, 2010–16
  • Figure: Daiichi Sankyo forecast global sales according to molecule type, 2010–16
  • Figure: Boehringer Ingelheim forecast global sales according to molecule type, 2010–16
  • Figure: AstraZeneca forecast global sales according to molecule type, 2010–16
  • Figure: Bayer forecast global sales according to molecule type, 2010–16
  • Figure: Roche forecast global sales according to molecule type, 2010–16

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